Monica Bessler Selected Research

Bone Marrow Failure Disorders

5/2014	Liver failure due to hepatic angiosarcoma in an adolescent with dyskeratosis congenita.
1/2009	TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements.
7/2007	Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production.
11/2006	Immunosuppressive therapy for acute porphyria: safety and efficacy in a patient with bone marrow failure.
7/2006	Low frequency of telomerase RNA mutations among children with aplastic anemia or myelodysplastic syndrome.
9/2004	Heterozygous telomerase deficiency in mouse and man: when less is definitely not more.
6/2004	A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria.
2/2004	Dyskeratosis congenita and telomerase.
6/2003	Human telomerase RNA mutations and bone marrow failure.

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Monica Bessler Research Topics

Disease

11	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 05/2014 - 09/2002
9	Bone Marrow Failure Disorders 05/2014 - 06/2003
7	Neoplasms (Cancer) 06/2017 - 06/2004
7	Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita) 04/2011 - 02/2004
6	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2015 - 07/2007
6	Autosomal Dominant Dyskeratosis Congenita 02/2008 - 02/2004
5	Hemolysis 01/2014 - 04/2004
5	Aplastic Anemia (Anemia, Hypoplastic) 10/2013 - 03/2003
3	Anemia 06/2017 - 02/2008
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2016 - 02/2004
2	Splenomegaly 06/2017 - 06/2011
2	Congenital Bone Marrow Failure Syndromes 02/2012 - 11/2005
2	idiopathic Aplastic anemia 09/2004 - 02/2004
1	Primary Myelofibrosis (Myelosclerosis) 06/2017
1	Pure Red-Cell Aplasia 01/2015
1	Macrocytic Anemia 01/2015
1	Enterocolitis 05/2014
1	Hemangiosarcoma (Angiosarcoma) 05/2014
1	Liver Failure 05/2014
1	Malaria 01/2014
1	Hoyeraal Hreidarsson syndrome 06/2013
1	Hypertension (High Blood Pressure) 05/2010
1	Pulmonary Hypertension 05/2010
1	Right Ventricular Dysfunction 05/2010
1	Fatigue 02/2008
1	Thrombocytopenia (Thrombopenia) 02/2008
1	Thromboembolism 12/2007
1	Cri-du-Chat Syndrome (5p- Syndrome) 10/2007
1	Osteosarcoma (Osteogenic Sarcoma) 07/2007
1	Neurologic Manifestations (Neurological Manifestations) 11/2006
1	Acute Intermittent Porphyria (Porphyria, Acute) 11/2006
1	Disease Progression 11/2006
1	Juvenile Myelomonocytic Leukemia 07/2006
1	Lymphopenia (Lymphocytopenia) 01/2005
1	Agammaglobulinemia (Hypogammaglobulinemia) 01/2005
1	Hemolytic Anemia 04/2004
1	Hemoglobinuria 04/2004
1	Delayed Hypersensitivity (Hypersensitivity, Type IV) 09/2002

Drug/Important Bio-Agent (IBA)

12	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2013 - 02/2004
10	telomerase RNA (bTR)IBA 01/2009 - 06/2003
6	Proteins (Proteins, Gene)FDA Link 01/2014 - 02/2004
5	RNA (Ribonucleic Acid)IBA 02/2008 - 02/2004
4	eculizumab FDA Link 05/2014 - 12/2007
4	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 06/2004 - 09/2002
4	GPI-Linked ProteinsIBA 06/2004 - 12/2002
3	Ribosomal Proteins (Ribosomal Protein)IBA 01/2015 - 07/2012
2	Complement Inactivating AgentsIBA 02/2008 - 12/2007
2	Complement System Proteins (Complement)IBA 01/2008 - 04/2004
2	Membrane Proteins (Integral Membrane Proteins)IBA 02/2004 - 09/2002
1	Messenger RNA (mRNA)IBA 06/2017
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015
1	Phosphotransferases (Kinase)IBA 01/2015
1	InterferonsIBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2015
1	ProteomeIBA 01/2015
1	MitogensIBA 01/2015
1	Infliximab (Remicade)FDA Link 05/2014
1	DysferlinIBA 01/2014
1	Pharmaceutical PreparationsIBA 01/2014
1	glucose-6-phosphate dehydrogenase A-IBA 01/2014
1	Oxidants (Oxidizing Agents)IBA 01/2014
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2014
1	EnzymesIBA 01/2014
1	Glutathione Transferase (Glutathione S-Transferase)IBA 10/2013
1	EpitopesIBA 10/2013
1	Biomarkers (Surrogate Marker)IBA 02/2012
1	HMGA2 ProteinIBA 06/2011
1	Erythropoietin FDA Link 06/2011
1	AntioxidantsIBA 04/2011
1	Arginine (L-Arginine)FDA Link 05/2010
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2010
1	pro-brain natriuretic peptide (1-76)IBA 05/2010
1	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2010
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 02/2008
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 02/2008
1	Small Interfering RNA (siRNA)IBA 07/2007
1	18S Ribosomal RNAIBA 07/2007
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2006
1	Heme (Haem)IBA 11/2006
1	NucleotidesIBA 07/2006
1	Immunoglobulin M (IgM)IBA 01/2005
1	Ribosomal RNAIBA 02/2004
1	CytokinesIBA 09/2003
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2003
1	Immunoglobulin G (IgG)IBA 09/2002
1	AntibodiesIBA 09/2002

Therapy/Procedure

6	Therapeutics 01/2016 - 02/2004
1	Kidney Transplantation 11/2006
1	Hematopoietic Stem Cell Transplantation 02/2004